Holly Hunter
Similar to her costar Jason Alexander, Holly Hunter also made her film debut in 1981's slasher flick The Burning—the film was arguably a rip-off of Friday the 13th, which came out one year earlier. Hunter played Sophie, a small role with few speaking lines. It wasn't until 1987 that Hunter truly broke into the scene with her Academy Award-nominated performance in Raising Arizona.
Justin Long
Jeepers Creepers (2001) was a low-budget horror movie with zero big names released at the very end of summer's dog days—but it still managed to launch Justin Long's acting career. The Victor Salva flick brought success to both Long and Salva, breaking box-office records across the nation. Salva was confident that the up-and-coming actor could come off as funny or genuinely terrified, depending on the scene.