Sheldon Cooper
Sheldon Cooper worked alongside Leonard as a theoretical physicist at CalTech. Despite Sheldon's belief that his intellect was superior to everyone else's, he often failed to recognize the nuance of social situations. Sheldon eventually became a Nobel Prizewinner alongside his wife, Amy.
Played by Jim Parsons
Jim Parsons is arguably the most successful member of The Big Bang Theory cast. Parsons has received several accolades for his performance, including four Emmy Awards and a Golden Globe Award. He married his husband, art director Todd Spiewak, in 2012.