George Clooney
Clooney won an Academy Award for Best Actor for his depiction of a CIA operative in the 2005 film Syriana. However, while he was on that set, a failed stunt sent Clooney to the hospital with a terrible spine injury. Clooney was plagued with horrible headaches that genuinely made him consider taking his own life...
Making it Worth the Pain
Clooney eventually got surgery for the injury that treated his headaches. Because of the stress and discomfort, Clooney dropped in weight and looked disheveled, so he was cast in Oceans Twelve as agent Robert Barnes, an ill special agent. Clooney looks back and views this portion of his life as a horrible whirlwind of discomfort that he wouldn't wish on his worst enemy.