Supergirl
In season 3 of this girl power show, Erica Durance was recast into Laura Benanti's role. Laura's Broadway schedule caused problems for the show, so she left. "We are so blessed that Erica has come aboard to offer her own interpretation of Kara’s mother," said executive producer Andrew Kreisberg, "We know Erica will continue the proud tradition of legacy actors joining our shows and creating new and exciting takes on classic DC characters."
Two and a Half Men
When you've only got two and a half men in a TV show, the recasting can be pretty noticeable. Take, for example, the recasting of the character Dolores Pasternak. Missi Pyle was originally in the role, but she was replaced by Alicia Witt. Then, Missi randomly returned with no explanation at the series' last episode. No one knows why really...