Doug Murphy
This pathologist on Scrubs started as a medical intern the same year as Turk, J.D., and Elliot, but he was a totally incompetent doctor, accidentally killing a number of his patients. His repeated exposure to death is what led him to become a pathologist. Dr Cox once noted that Doug had "killed so many patients, I'm starting to think that he just might be a government operative."
Ned Rochlin
Ned Rochlin in Our Idiot Brother is a man of great intentions and poor execution. To start off, Ned is arrested for selling weed to a uniformed police officer. Although he isn't so much a slacker as he is dumb as a rock, Ned's efforts are eventually channeled into opening up a small homemade candle shop, which is the only job he's truly capable of holding.