Drew Barrymore
Drew Barrymore completely changed everything with her quick cameo in the first Scream film. After all, people still dress up as her for Halloween! She was originally asked to play the lead role of Sidney Prescott but opted for this small intro scene instead.
"It was amazing for me because when I watched the film, I was actually scared," she said of Scream. "I mean, it is so scary that even though I was in it -- I was there, I knew everything that was going on, the mechanics and everything -- it was still just a flat-out scary movie.