Elena Anaya had the mask glued to her face during the entire day. That meant that she couldn't eat or drink anything until they wrapped for the day. She said that the process of putting it on and taking it off was painful, but it was worth it.
Voldemort - Ralph Fiennes
For an entire generation of people, Voldemort is the evilest villain in existence. Ralph Fiennes transformed into the character just like everyone else, minus the CGI makeup for the removal f his nose. What good would it do if He Who Must Not Be Named had a nose? That was the only CGI part of his transformation, everything else was real makeup.
Pinhead - Doug Bradley
Pinhead is the main villain in the Hellraiser franchise. Doug Bradley played the main Cenobite (extra-dimensional beings who are mutilated and brainwashed into torturing humans for all eternity in the Labyrinth) from 1987 until 2005. He finally turned down a role after he felt like the films had been played out and that it was just a cheap cash grab.