Octavia Spencer
This esteemed film veteran has over 70 credits to her name, and that includes 2009's Drag Me to Hell as an unnamed bank teller. Drag Me to Hell was Spencer's first foray into the genre. In 2019, Spencer starred in Ma, a psychological horror film. That's a step up from bank teller, certainly.
Chris Hemsworth
Before wielding a magical hammer alongside his Avengers crew, Chris Hemsworth played Curt Vaughan, the stereotypical jock in Joss Whedon's horror-comedy The Cabin in the Woods (2011). Hemsworth claimed that he "blew" his first audition with director Kenneth Branagh for Thor, but when Whedon learned of the Aussie's interest in the role, he made a few calls, effectively sealing the deal. Without The Cabin in the Woods, Chris Hemsworth never would have become the face of Thor.