Laura Dern, Billy Bob Thornton, and Angelina Jolie
Laura Dern and Billy Bob Thornton first met in 1997 after guest-starring on the infamous episode of Ellen in which DeGeneres' character comes out as a lesbian. They dated afterward and even moved in together, but things quickly went south.
While Laura was away shooting a movie, Billy Bob met and fell in love with Angelina Jolie. The two were wed before Laura even returned from her trip. "I left our home to work on a movie, and while I was away, my boyfriend got married, and I've never heard from him again," she said in 2000.